Devloo-Delva, F. & Burridge, C.P. & Kyne, P.M. & Brunnschweiler, J.M. & Chapman, D.D. & Charvet, P. & Chen, X. & Cliff, G. & Daly, R. & Drymon, J.M. & Espinoza, M. & Fernando, D. & Barcia, L.G. & Glaus, K. & González-Garza, B.I. & Grant, M.I. & Gunasekera, R.M. & Hernandez, S. & Hyodo, S. & Jabado, R.W. & Jaquemet, S. & Johnson, G. & Ketchum, J.T. & Magalon, H. & Marthick, J.R. & Mollen, F.H. & Mona, S. & Naylor, G.J.P. & Nevill, J.E.G. & Phillips, N.M. & Pillans, R.D. & Postaire, B.D. & Smoothey, A.F. & Tachihara, K. & Tillet, B.J. & Valerio-Vargas, J.A. & Feutry, P. (2023)
From rivers to ocean basins: The role of ocean barriers and philopatry in the genetic structuring of a cosmopolitan coastal predator. Ecology and Evolution, 13(2), Article e9837
DOI: 10.1002/ece3.9837

Wang, C. & Ye, P.Y. & Pillans, R. & Chen, X. & Wang, J.J. & Feutry, P. (2023)
Evolution of the Critically Endangered Green Sawfish Pristis zijsron (Rhinopristiformes, Pristidae), Inferred from the Whole Mitochondrial Genome. Genes, 14(11), Article 2052
DOI: 10.3390/genes14112052

Postaire, B.D. & Devloo-Delva, F. & Brunnschweiler, J.M. & Charvet, P. & Chen, X. & Cliff, G. & Daly, R. & Drymon, J.M. & Espinoza, M. & Fernando, D. & Glaus, K. & Grant, M.I. & Hernandez, S. & Hyodo, S. & Jabado, R.W. & Jaquemet, S. & Johnson, G. & Naylor, G.J.P. & Nevill, J.E.G. & Pathirana, B.M. & Pillans, R.D. & Smoothey, A.F. & Tachihara, K. & Tillet, B.J. & Valerio-Vargas, J.A. & Lesturgie, P. & Magalon, H. & Feutry, P. & Mona, S. (2023)
Global genetic diversity and historical demography of the Bull Shark. Journal of Biogeography, in press
DOI: 10.1111/jbi.14774

Qi, J.W. & Shi, F.L. & Zhang, B.W. & Chen, X. & Xing, J. & Furumitsu, K. & Corush, J.B. & Yamaguchi, A. & Zhang, J. (2022)
Insights into genetic variation and demographic history of sharpnose rays: examinations of three species of Telatrygon (Elasmobranchii, Dasyatidae) from the Indo-West Pacific. Integrative Zoology, 17(6), 1063–1077
DOI: 10.1111/1749-4877.12614

Wang, C. & Lai, T.H. & Ye, P.Y. & Yan, Y.R. & Feutry, P. & He, B.Y. & Huang, Z.J. & Zhu, T. & Wang, J.J. & Chen, X. (2022)
Novel duplication remnant in the first complete mitogenome of Hemitriakis japanica and the unique phylogenetic position of family Triakidae. Gene, 820, Article 146232
DOI: 10.1016/j.gene.2022.146232

Devloo-Delva, F. & Burridge, C.P. & Kyne, P.M. & Brunnschweiler, J.M. & Chapman, D.D. & Charvet, P. & Chen, X. & Cliff, G. & Daly, R. & Drymon, J.M. & Espinoza, M. & Fernando, D. & Barcia, L.G. & Glaus, K. & Grant, M.I. & Gunasekera, R.M. & Hernandez, S.I. & Hyodo, S. & Jabado, R.W. & Jaquemet, S. & Johnson, G. & Magalon, H. & Marthick, J.R. & Mollen, F.H. & Mona, S. & Naylor, G.J.P. & Nevill, J.E.G. & Phillips, N.M. & Pillans, R.D. & Postaire, B.D. & Smoothey, A.F. & Tachihara, K. & Tillet, B.J. & Valerio, J. & Feutry, P. (2020)
From rivers to ocean basins – Global genetic population structure of the bull shark [Abstract]. In OCS Virtual Conference, Nov 3 & 4, Program & Abstracts: 8

Chen, X. & Wang, J.J. & Ai, W.M. & Chen, H. & Lin, H.D. (2018)
Phylogeography and genetic population structure of the spadenose shark (Scoliodon macrorhynchos) from the Chinese coast. Mitochondrial DNA Part A, 29(7), 1100–1107
DOI: 10.1080/24701394.2017.1413363

Kyne, P.M. & Wang, J.J. & Xiang, D. & Chen, X. & Feutry, P. (2018)
The phylogenomic position of the Critically Endangered Largetooth Sawfish Pristis pristis (Rhinopristiformes, Pristidae), inferred from the complete mitochondrial genome. Mitochondrial DNA Part B, 3(2), 972–973
DOI: 10.1080/23802359.2018.1501315

Wang, J.J. & Chen, H. & Lin, L.L. & Ai, W.M. & Chen, X. (2017)
Mitochondrial genome and phylogenetic position of the tawny nurse shark (Nebrius ferrugineus). Mitochondrial DNA Part A, 28(1–2), 141–142
DOI: 10.3109/19401736.2015.1111361

Chen, X. & Liu, M. & Xiao, J. & Yang, W. & Peng, Z. (2016)
Complete mitochondrial genome of the hardnose shark Carcharhinus macloti (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 27(2), 1090–1091
DOI: 10.3109/19401736.2014.930836

Chen, X. & Sonchaeng, P. & Yuvanatemiya, V. & Nuangsaeng, B. & Ai, W. (2016)
Complete mitochondrial genome of the whitetip reef shark Triaenodon obesus (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 27(2), 947–948
DOI: 10.3109/19401736.2014.926499

Feutry, P. & Pillans, Rd. & Kyne, P.M. & Chen, X. (2016)
Complete mitogenome of the Graceful Shark Carcharhinus amblyrhynchoides (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 27(1), 314–315
DOI: 10.3109/19401736.2014.892094

Chen, X. & Ai, W.M. & Pan, L. & Shi, X. (2016)
Complete mitochondrial genome of the largest living fish: whale shark Rhincodon typus (Orectolobiformes: Rhincodontidae). Mitochondrial DNA, 27(1), 425–426
DOI: 10.3109/19401736.2014.898288

Chen, X. & Shen, X.J. & Arunrugstichai, S. & Ai, W.M. & Xiang, D. (2016)
Complete mitochondrial genome of the blacktip reef shark Carcharhinus melanopterus (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 27(2), 873–874
DOI: 10.3109/19401736.2014.919483

Chen, X. & Xiang, D. & Peng, X. & Ai, W.M. & Chen, H. (2016)
The complete mitochondrial genome of the spinner shark Carcharhinus brevipinna. Mitochondrial DNA, 27(3), 1666–1667
DOI: 10.3109/19401736.2014.958720

Feutry, P. & Every, S.L. & Kyne, P.M. & Sun, R. & Chen, X. (2016)
Complete mitochondrial genome of the Pigeye Shark Carcharhinus amboinensis (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 27(3), 2429–2130
DOI: 10.3109/19401736.2014.982590

Chen, X. & Lin, L. & Chen, H. & Xiang, D. & Ai, W. (2016)
Complete mitochondrial genome of the Indonesian whaler shark Carcharhinus tjutjot. Mitochondrial DNA, 27(6), 3962–3963
DOI: 10.3109/19401736.2014.989505

Periasamy, R. & Chen, X. & Ingole, B. & Liu, W. (2016)
Complete mitochondrial genome of the Spadenose shark Scoliodon laticaudus (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 27(5), 3248–3249
DOI: 10.3109/19401736.2015.1007368

Chen, X. & Wiley, T.R. & Kyne, P.M. & Feutry, P. (2016)
Complete mitochondrial genome of the Critically Endangered Smalltooth Sawfish Pristis pectinata (Rajiformes: Pristidae). Mitochondrial DNA, 27(5), 3331–3332
DOI: 10.3109/19401736.2015.1018208

Chen, X. & Kyne, P.M. & Pillans, R.D. & Feutry, P. (2016)
Complete mitochondrial genome of the Endangered Narrow Sawfish Anoxypristis cuspidata (Rajiformes: Pristidae). Mitochondrial DNA, 27(3), 1589–1590
DOI: 10.3109/19401736.2014.1003898

Chen, H. & Lin, L. & Chen, X. & Ai, W.M. & Chen, S. (2016)
Complete mitochondrial genome and the phylogenetic position of the Blotchy swell shark Cephaloscyllium umbratile. Mitochondrial DNA, 27(4), 3045–3047
DOI: 10.3109/19401736.2015.1063127

Wang, J. & Chen, H. & Lin, L. & Ai, W.M. & Chen, X. (2016)
Mitochondrial genome and phylogenetic position of the sliteye shark Loxodon macrorhinus. Mitochondrial DNA, 27(6), 4288–428
DOI: 10.3109/19401736.2015.1082099

Mai, Q. & Li, W. & Chen, H. & Ai, W. & Chen, X. (2016)
Complete mitochondrial genome and phylogenetic position of the Sicklefin weasel shark Hemigaleus microstoma. Mitochondrial DNA, 27(5), 3491–3492
DOI: 10.3109/19401736.2015.1066363

Chen, X. & Xiang, D. & Arunrugstichai, S. & Cai, L. & Xu, Y. (2016)
Complete mitochondrial genome of the mangrove whipray Himantura granulata (Myliobatiformes: Dasyatidae). Mitochondrial DNA, 27(1), 1–2
DOI: 10.3109/19401736.2013.865178

Chen, X. & Ai, W.M. & Xiang, D. & Pan, L. & Shi, X. (2016)
Complete mitogenome of the brown guitarfish Rhinobatos schlegelii (Rajiformes, Rhinobatidae). Mitochondrial DNA, 27(1), 310–311
DOI: 10.3109/19401736.2014.892091

Chen, X. & Ai, W.M. & Xiang, D. & Shi, X. (2016)
Mitochondrial genome of the longtail butterfly ray Gymnura poecilura (Myliobatiformes: Gymnuridae). Mitochondrial DNA, 27(1), 696–697
DOI: 10.3109/19401736.2014.913148

Chen, X. & Peng, Z. & Pan, L. & Shi, X. & Cai, L. (2016)
Mitochondrial genome of the spotless smooth-hound Mustelus griseus (Carcharhiniformes: Triakidae). Mitochondrial DNA, 27(1), 78–79
DOI: 10.3109/19401736.2013.873908

Li, W. & Chen, X. & Liu, W. & Sun, R. & Zhou, H. (2016)
Complete mitochondrial genome of the Yellow-spotted skate Okamejei hollandi (Rajiformes: Rajidae). Mitochondrial DNA, 27(4), 2883–2884
DOI: 10.3109/19401736.2015.1060419

Feutry, P. & Kyne, P.M. & Peng, Z.Q. & Pan, L.H. & Chen, X. (2016)
Complete mitochondrial genome of the Freshwater Whipray Himantura dalyensis. Mitochondrial DNA, 27(3), 1589–1590
DOI: 10.3109/19401736.2014.958682

Chen, H. & Chen, X. & Gu, X. & Wan, H. & Chen, Xi. & Ai, W. (2016)
The phylogenomic position of the smooth lanternshark Etmopterus pusillus (Squaliformes: Etmopteridae) inferred from the mitochondrial genome. Mitochondrial DNA Part B, 1(1), 341–342
DOI: 10.1080/23802359.2016.1172274

Chen, H. & Chen, X. & Yu, H. & Ai, W. (2016)
Complete mitochondrial genome and the phylogenetic position of theTaiwan spurdog shark Squalus formosus (Squaliformes: Squalidae). Mitochondrial DNA Part B, 1(1), 419–420
DOI: 10.1080/23802359.2016.1176884

Chen, H. & Ding, W.X. & Chen, X. & Ai, W. (2016)
Complete mitochondrial genome and the phylogenetic position of the smalleye pygmy shark Squaliolus aliae (Squaliformes: Dalatiidae). Mitochondrial DNA Part B, 1(1), 304–305
DOI: 10.1080/23802359.2016.1167639

Huang, X. & Yu, J. & Chen, H. & Chen, X. & Wang, J. (2016)
Complete mitochondrial genome and the phylogenetic position of the snaggletooth shark Hemipristis elongata (Carcharhiniformes: Hemigaleidae). Mitochondrial DNA Part B, 1(1), 538–539
DOI: 10.1080/23802359.2016.1197074

Chen, H. & Ding, W. & Shan, L. & Chen, X. & Ai, W. (2016)
Complete mitochondrial genome and the phylogenetic position of the blackspotted catshark Halaelurus burgeri (Carcharhiniformes: Scyliorhinidae). Mitochondrial DNA Part B, 1(1), 369–370
DOI: 10.1080/23802359.2016.1168722

Chen, H. & Yu, H. & Si, R. & Chen, X. & Ai, W. (2016)
Complete mitochondrial genome and the phylogenetic position of the graceful catshark Proscyllium habereri (Carcharhiniformes: Proscylliidae). Mitochondrial DNA Part B, 1(1), 268–269
DOI: 10.1080/23802359.2016.1159934

Si, R. & Chen, X. & Chen, H. & Ai, W. (2016)
Complete mitochondrial genome and the phylogenetic position of the Leadhued skate Notoraja tobitukai (Rajiformes: Arhynchobatidae). Mitochondrial DNA Part B, 1(1), 787–788
DOI: 10.1080/23802359.2016.1192514

Si, R. & Ding, W. & Ai, W.M. & Chen, X. (2016)
Complete mitochondrial genome and the phylogenetic position of the Borneo leg skate Sinobatis borneensis (Rajiformes: Anacanthobatidae). Mitochondrial DNA Part B, 1(1), 443–444
DOI: 10.1080/23802359.2016.1180560

Si, R. & Ding, W. & Chen, H. & Chen, X. & Ai, W. (2016)
Complete mitochondrial genome and the phylogenetic position of the White-spotted guitarfish Rhynchobatus australiae (Rajiformes, Rhinobatidae). Mitochondrial DNA Part B, 1(1), 315–317
DOI: 10.1080/23802359.2016.1172041

Chen, X. & Cai, J.B. & Ding, W.Y. & Xiang, D. & Ai, W.M. (2016)
Complete mitochondrial genome of the Sharpnose stingray Himantura gerrardi (Myliobatiformes: Dasyatidae). Mitochondrial DNA Part A, 27(6), 3989–3990
DOI: 10.3109/19401736.2014.989518

Chen, H. & Chen, X. & Ai, W.M. & Wang, J.J. (2016)
Complete mitochondrial genome and the phylogenetic position of the zebra shark (Stegostoma fasciatum). Mitochondrial DNA Part B, 1(1), 105–106
DOI: 10.1080/23802359.2015.1137846

Si, R.R. & Chen, H. & Ai, W.M. & Chen, X. & Chen, S.B. (2016)
Complete mitochondrial genome and the phylogenetic position of the Bowmouth guitarfish Rhina ancylostoma (Rajiformes, Rhinobatidae). Mitochondrial DNA Part B, 1(1), 270–272
DOI: 10.1080/23802359.2016.1159935

Si, R.R. & Ding, W.Y. & Yu, J.Q. & Chen, X. & Ai, W.M. (2016)
Complete mitochondrial genome and the phylogenetic position of the Jenkins whipray Himantura jenkinsii (Myliobatiformes, Dasyatidae). Mitochondrial DNA Part B, 1(1), 297–298
DOI: 10.1080/23802359.2016.1166085

Feutry, P. & Kyne, P.M. & Chen, X. (2016)
The phylogenomic position of the Winghead Shark Eusphyra blochii (Carcharhiniformes, Sphyrnidae) inferred from the mitochondrial genome. Mitochondrial DNA Part B, 1(1), 386–387
DOI: 10.1080/23802359.2016.1172049

Wang, J.J. & Si, R.R. & Chen, H. & Chen, X. (2016)
The phylogenomic position of the smalleye whip ray Himantura microphthalma (Myliobatiformes: Dasyatidae) inferred from the mitochondrial genome. Mitochondrial DNA Part B, 1(1), 564–565
DOI: 10.1080/23802359.2016.1186519

Chen, X. & Liu, M. & Peng, Z. & Shi, X. (2015)
Mitochondrial genome of the bull shark Carcharhinus leucas (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 26(6), 813–814
DOI: 10.3109/19401736.2013.855906

Feutry, P. & Grewe, Pm. & Kyne, P.M. & Chen, X. (2015)
Complete mitogenomic sequence of the Critically Endangered Northern River Shark Glyphis garricki (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 26(6), 855–856
DOI: 10.3109/19401736.2013.861428

Li, N. & Chen, X. & Sun, D. & Song, N. & Lin, Q. & Gao, T. (2015)
Phylogeography and population structure of the red stingray, Dasyatis akajei inferred by mitochondrial control region. Mitochondrial DNA, 26(4), 505–513
DOI: 10.3109/19401736.2013.861423

Chen, X. & Peng, Z. & Cai, L. & Xu, Y. (2015)
Mitochondrial genome of the spot-tail shark Carcharhinus sorrah (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 26(5), 734–735
DOI: 10.3109/19401736.2013.845764

Chen, X. & Xiang, D. & Ai, W.M. & Shi, X. (2015)
Complete mitochondrial genome of the blue shark Prionace glauca (Elasmobranchii: Carcharhiniformes). Mitochondrial DNA, 26(2), 313–314
DOI: 10.3109/19401736.2013.825790

Chen, X. & Ai, W.M. & Shi, X. & Gao, T. (2015)
Mitochondrial genome of the ringstraked guitarfish Rhinobatos hynnicephalus (Elasmobranchii: Rajiformes). Mitochondrial DNA, 26(4), 653–654
DOI: 10.3109/19401736.2013.836520

Feutry, P. & Kyne, P.M. & Grewe, P.M. & Chen, X. & Liu, M. (2015)
Whole mitogenome of the Endangered dwarf sawfish Pristis clavata (Rajiformes: Pristidae). Mitochondrial DNA, 26(2), 329–330
DOI: 10.3109/19401736.2013.830297

Chen, X. & Xiang, D. & Ai, W.M. & Shi, X. (2015)
Complete mitochondrial genome of the pelagic thresher Alopias pelagicus (Lamniformes: Alopiidae) Mitochondrial DNA, 26(2), 323–4
DOI: 10.3109/19401736.2013.830294

Chen, X. & Liu, M. & Xiang, D. & Ai, W. (2015)
Complete mitochondrial genome of the Japanese wobbegong Orectolobus japonicus (Orectolobiformes: Orectolobidae). Mitochondrial DNA, 26(1), 153–154
DOI: 10.3109/19401736.2013.819499

Chen, X. & Xiang, D. & Xu, Y. & Shi, X. (2015)
Complete mitochondrial genome of the scalloped hammerhead Sphyrna lewini (Carcharhiniformes: Sphyrnidae). Mitochondrial DNA, 26(4), 621–622
DOI: 10.3109/19401736.2013.834432

Feutry, P. & Kyne, P.M. & Pillans, R.D. & Chen, X. & Marthick, J. & Morgan, D.L. & Grewe, P.M. (2015)
Whole mitogenome sequencing refines the population structure of the Critically Endangered sawfish Pristis pristis (Linnaeus, 1758). Marine Ecology Progress Series, 533, 237–244
DOI: 10.3354/meps11354

Chen, X. & Yu, J. & Zhang, S. & Ding, W. & Xiang, D. (2014)
Complete mitochondrial genome of the tiger shark Galeocerdo cuvier (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 25(6), 441–442
DOI: 10.3109/19401736.2013.809450

Li, Y. & Gong, Y. & Chen, X. & Dai, X. & Zhu, J. (2014)
Trophic ecology of sharks in the mid-east pacific ocean inferred from stable isotopes. Journal of Ocean University of China, 13(2), 278–282
DOI: 10.1007/s11802-014-2071-1

Chen, X. & Ai, W.M. & Xiang, D. & Chen, S. (2014)
Complete mitochondrial genome of the red stingray Dasyatis akajei (Myliobatiformes: Dasyatidae). Mitochondrial DNA, 25(1), 37–38
DOI: 10.3109/19401736.2013.779262

Chen, X. & Zhou, Z. & Pichai, S. & Huang, X. & Zhang, H. (2014)
Complete mitochondrial genome of the brownbanded bamboo shark Chiloscyllium punctatum. Mitochondrial DNA, 25(2), 113–114
DOI: 10.3109/19401736.2013.786710

Chen, X. & Peng, X. & Zhang, P. & Yang, S. & Liu, M. (2014)
Complete mitochondrial genome of the spadenose shark (Scoliodon macrorhynchos). Mitochondrial DNA, 25(2), 91–92
DOI: 10.3109/19401736.2013.784751

Chen, X. & Peng, X. & Huang, X. & Xiang, D. (2014)
Complete mitochondrial genome of the Zebra bullhead shark Heterodontus zebra (Heterodontiformes: Heterodontidae). Mitochondrial DNA, 25(4), 280–281
DOI: 10.3109/19401736.2013.796514

Chen, X. & Liu, M. & Grewe, P.M. & Kyne, P.M. & Feutry, P. (2014)
Complete mitochondrial genome of the Critically Endangered speartooth shark Glyphis glyphis (Carcharhiniformes: Carcharhinidae). Mitochondrial DNA, 25(6), 431–432
DOI: 10.3109/19401736.2013.809443

Feutry, P. & Kyne, P.M. & Pillans, R.D. & Chen, X. & Naylor, G.J.P. & Grewe, P.M. (2014)
Mitogenomics of the Speartooth Shark challenges ten years of control region sequencing. BMC Evolutionary Biology, 14(1), Article 232
DOI: 10.1186/s12862-014-0232-x

Chen, X. & Xiang, D. & Yu, J. & Ding, W. & Zhang, S. (2014)
Complete mitochondrial genome of the blue-spotted stingray Neotrygon kuhlii (Myliobatiformes: Dasyatidae). Mitochondrial DNA, 25(6), 429–430
DOI: 10.3109/19401736.2013.809442

Chen, X. & Ai, W.M. & Xiang, D. & Chen, S. (2013)
Mitochondrial genome of blotched fantail ray Taeniura meyeni (Myliobatiformes: Dasyatidae). Mitochondrial DNA, 24(6), 663–664
DOI: 10.3109/19401736.2013.773320

Chen, X. & Ai, W.M. & Ye, L. & Wang, X.H. & Lin, C.W. & Yang, S.Y. (2013)
The complete mitochondrial genome of the grey bamboo shark (Chiloscyllium griseum) (Orectolobiformes: Hemiscylliidae): genomic characterization and phylogenetic application. Acta Oceanologica Sinica, 32(4), 59–65
DOI: 10.1007/s13131-013-0298-0

Zhang, B. & Zeng, X. & Chen, X. & Li, Z. & Zhou, P. & Zhang, M. (2013)
New Materials of Fish Microfossils from the Middle Permian in West Hubei. Acta Micropalaeontologica Sinica, 30(2), 184–190

Chen, X. & Ai, W.M. & Xiang, D. & Chen, Y. & Chen, S. (2013)
Complete mitogenome of the pale-edged stingray Dasyatis zugei (Myliobatiformes: Dasyatidae). Mitochondrial DNA, 24(3), 196–198
DOI: 10.3109/19401736.2012.744982

Zhang, B. & Chen, X. & Cheng, L. & Zhang, M. (2012)
Middle Triassic (Ladinian) Elasmobranch Scales From The Southwestern Guizhou, China. Acta Micropalaeontologica Sinica, 29(1), 52–61

Zhu, J. & Dai, X. & Xu, L. & Chen, X. & Chen, Y. (2011)
Reproductive biology of female blue shark Prionace glauca in the southeastern Pacific Ocean. Environmental Biology of Fishes, 91(1), 95–102
DOI: 10.1007/s10641-010-9763-1

Huang, H.-Q. & Xiao, Z.-Q. & Chen, X. & Lin, Q.-M. & Cai, Z.-W. & Chen, P. (2004)
Characteristics of structure, composition, mass spectra, and iron release from the ferritin of shark liver (Sphyrna zygaena). Biophysical Chemistry, 111(3), 213–222
DOI: 10.1016/j.bpc.2004.06.002