Jia, Z. & Feng, J.H. & Dooley, H. & Zou, J. & Wang, J.Y. (2023)
The first crystal structure of CD8αα from a cartilaginous fish. Frontiers in Immunology, 14, Article 1156219
DOI: 10.3389/fimmu.2023.1156219
Chen, W.H. & Hajduczki, A. & Martinez, E.J. & Bai, H.J. & Matz, H. & Hill, T.M. & Lewitus, E. & Chang, W.C. & Dawit, L. & Peterson, C.E. & Rees, P.A. & Ajayi, A.B. & Golub, E.S. & Swafford, I. & Dussupt, V. & David, S. & Mayer, S.V. & Soman, S. & Kuklis, C. & Corbitt, C. & King, J. & Choe, M. & Sankhala, R.S. & Thomas, P.V. & Zemil, M. & Wieczorek, L. & Hart, T. & Duso, D. & Kummer, L. & Yan, L.Y. & Sterling, S.L. & Laing, E.D. & Broder, C.C. & Williams, J.K. & Davidson, E. & Doranz, B.J. & Krebs, S.J. & Polonis, V.R. & Paquin-Proulx, D. & Rolland, M. & Reiley, W.W. & Gromowski, G.D. & Modjarrad, K. & Dooley, H. & Joyce, M.G. (2023)
Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity. Nature Communications, 14(1), Article 580
DOI: 10.1038/s41467-023-36106-x
Matz, H. & Taylor, R.S. & Redmond, A.K. & Hill, T.M. & Daniels, R.R. & Beltran, M. & Henderson, N.C. & Macqueen, D.J. & Dooley, H. (2023)
Organized B cell sites in cartilaginous fishes reveal the evolutionary foundation of germinal centers. Cell Reports, 42(7), Article 112664
DOI: 10.1016/j.celrep.2023.112664
Bakke, F.K. & Gundappa, M.K. & Matz, H. & Stead, D.A. & Macqueen, D.J. & Dooley, H. (2022)
Exploration of the Nurse Shark (Ginglymostoma cirratum) Plasma Immunoproteome Using High-Resolution LC-MS/MS. Frontiers in Immunology, 13, Article 873390
DOI: 10.3389/fimmu.2022.873390
Redmond, A.K. & Pettinello, R. & Bakke, F.K. & Dooley, H. (2022)
Sharks Provide Evidence for a Highly Complex TNFSF Repertoire in the Jawed Vertebrate Ancestor. Journal of Immunology, 209(9), 1713–1723
DOI: 10.4049/jimmunol.2200300
Matz, H. & Munir, D. & Logue, J. & Dooley, H. (2021)
The immunoglobulins of cartilaginous fishes. Developmental and Comparative Immunology, 115, Article 103873
DOI: 10.1016/j.dci.2020.103873
Tan, M. & Redmond, A.K. & Dooley, H. & Nozu, R. & Sato, K. & Kuraku, S. & Koren, S. & Phillippy, A.M. & Dove, A.D.M. & Read, T. (2021)
The whale shark genome reveals patterns of vertebrate gene family evolution. Elife, 10, Article e65394
DOI: 10.7554/eLife.65394
Eve, O. & Matz, H. & Dooley, H. (2020)
Proof of long-term immunological memory in cartilaginous fishes Developmental and Comparative Immunology, 108, Article 103674
DOI: 10.1016/j.dci.2020.103674
Redmond, A.K. & Zou, J. & Secombes, C.J. & Macqueen, D.J. & Dooley, H. (2019)
Discovery of All Three Types in Cartilaginous Fishes Enables Phylogenetic Resolution of the Origins and Evolution of Interferons. Frontiers in Immunology, 10, Article 1558
DOI: 10.3389/fimmu.2019.01558
Pettinello, R. & Redmond, A.K. & Secombes, C.J. & Macqueen, D.J. & Dooley, H. (2017)
Evolutionary history of the T cell receptor complex as revealed by small-spotted catshark (Scyliorhinus canicula). Developmental and Comparative Immunology, 74, 125–135
DOI: 10.1016/j.dci.2017.04.015
Li, R. & Redmond, A.K. & Wang, T. & Bird, S. & Dooley, H. & Secombes, C.J. (2015)
Characterisation of the TNF superfamily members CD40L and BAFF in the small-spotted catshark (Scyliorhinus canicula). Fish & Shellfish Immunology, 47(1), 381–389
DOI: 10.1016/j.fsi.2015.09.033
Crouch, K. & Smith, L.E. & Williams, R. & Cao, W. & Lee, M. & Jensen, A. & Dooley, H. (2014)
Corrigendum to “Humoral immune response of the small-spotted catshark, Scyliorhinus canicula”. Fish & Shellfish Immunology, 35(2), 623
DOI: 10.1016/j.fsi.2013.05.011
Dooley, H. (2014)
Athena and the Evolution of Adaptive Immunity. In S.L. Smith, R.B. Sim, M.F. Flajnik (Eds.) Immunobiology of the Shark (pp. 29–50). CRC Press
Crouch, K. & Smith, L.E. & Williams, R. & Cao, W. & Lee, M. & Jensen, A. & Dooley, H. (2013)
Humoral immune response of the small-spotted catshark, Scyliorhinus canicula. Fish & Shellfish Immunology, 34(5), 1158–1169
DOI: 10.1016/j.fsi.2013.01.025
Li, R. & Wang, T. & Bird, S. & Zou, J. & Dooley, H. & Secombes, C.J. (2013)
B cell receptor accessory molecule CD79α: Characterisation and expression analysis in a cartilaginous fish, the spiny dogfish (Squalus acanthias). Fish & Shellfish Immunology, 34(6), 1404–1415
DOI: 10.1016/j.fsi.2013.02.015
Castro, C.D. & Ohta, Y. & Dooley, H. & Flajnik, M.F. (2013)
Noncoordinate expression of J-chain and Blimp-1 define nurse shark plasma cell populations during ontogeny. European Journal of Immunology, 43(11), 3061–3075
DOI: 10.1002/eji.201343416
Li, R. & Dooley, H. & Wang, T. & Secombes, C.J. & Bird, S. (2012)
Characterisation and expression analysis of B-cell activating factor (BAFF) in spiny dogfish (Squalus acanthias): Cartilaginous fish BAFF has an unique extra exon that may impact receptor binding. Developmental and Comparative Immunology, 36(4), 707–717
DOI: 10.1016/j.dci.2011.11.010
Smith, L.E. & Crouch, K. & Cao, W. & Müller, M.R. & Wu, L. & Steven, J. & Lee, M. & Liang, M. & Flajnik, M.F. & Shih, H.H. & Barelle, C.J. & Paulsen, J. & Gill, D.S. & Dooley, H. (2012)
Characterization of the immunoglobulin repertoire of the spiny dogfish (Squalus acanthias). Developmental and Comparative Immunology, 36(4), 665–679
DOI: 10.1016/j.dci.2011.10.007
Müller, M.R. & O'Dwyer, R. & Kovaleva, M. & Rudkin, F. & Dooley, H. & Barelle, C.J. (2012)
Generation and Isolation of Target-Specific Single-Domain Antibodies from Shark Immune Repertoires. Methods in Molecular Biology, 907, 177–194
DOI: 10.1007/978-1-61779-974-7_9
Goodchild, S.A. & Dooley, H. & Schoepp, R.J. & Flajnik, M. & Lonsdale, S.G. (2011)
Isolation and characterisation of Ebolavirus- specific recombinant antibody fragments from murine and shark immune libraries. Molecular Immunology, 48(15–16), 2027–2037
DOI: 10.1016/j.molimm.2011.06.437
Flajnik, M.F. & Dooley, H. (2009)
The generation and selection of single-domain, v region libraries from nurse sharks. Methods in Molecular Biology, 562, 71–82
Stanfield, R.L. & Dooley, H. & Verdino, P. & Flajnik, M.F. & Wilson, I.A. (2007)
Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding. Journal of Molecular Biology, 367(2), 358–372
DOI: 10.1016/j.jmb.2006.12.045
Dooley, H. & Flajnik, M.F. (2006)
Antibody repertoire development in cartilaginous fish. Developmental and Comparative Immunology, 30(1–2), 43–56
DOI: 10.1016/j.dci.2005.06.022
Dooley, H. & Flajnik, M.F. (2005)
Shark immunity bites back: affinity maturation and memory response in the nurse shark, Ginglymostoma cirratum. European Journal of Immunology, 35(3), 936–945
DOI: 10.1002/eji.200425760
Rumfelt, L.L. & Lohr, R.L. & Dooley, H. & Flajnik, M.F. (2004)
Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark. BMC Immunology, 5(1), Article 8
DOI: 10.1186/1471-2172-5-8
Dooley, H. & Flajnik, M.F. & Porter, A.J. (2003)
Selection and characterization of naturally occurring single-domain (IgNAR) antibody fragments from immunized sharks by phage display. Molecular Immunology, 40(1), 25–33
DOI: 10.1016/S0161-5890(03)00084-1